New research may open a window to treat an aggressive form of acute B-cell lymphoblastic leukemia
Survival has greatly improved in children with acute lymphocytic leukemia (ALL). But some form of ALL that occurs primarily in infants is still very lethal, with a survival rate below 50%: acute B-cell lymphoblastic leukemia with rearrangements of the mixed-lineage leukemia gene, or MLL B-ALL. Something about the biology of this type of leukemia …