More cases of smallpox have been reported, bringing the total to 470 in the UK.
The UK Health Security Agency (UKHSA) has said that 104 more cases have been confirmed in England today.
There are currently 452 confirmed cases in England, 12 in Scotland, two in Northern Ireland and four in Wales.
Most cases so far have been in gay men, bisexuals or men who have sex with men.
The UKHSA has issued a new warning to anyone with a blistering rash who should contact a sexual health clinic if they have also had close contact, including sexual contact, with someone who has had or may have had had monkeypox in the last three weeks.
People are also advised to contact a clinic if they have traveled to West or Central Africa during the past three weeks.
Monkeypox has become a notifiable disease in England, which means that all doctors must notify local health authorities of suspicious cases. Laboratories must also inform the UKHSA if the virus is identified in a sample.
The disease is spread by close contact and was first found in monkeys.
It is found mainly in West and Central Africa and only spreads very occasionally to other places.
More than 30 countries where monkeypox is not endemic have now reported outbreaks of viral disease.
Read more: The “rapid evolution” monkeypox outbreak and the actions needed to stop the spread warn WHO. How is smallpox caught, what are the symptoms and how easily is it transmitted? People with symptoms should not have sex, according to a new UK guide
The number of confirmed cases worldwide is close to 1,500, most in Europe.
Although the United Kingdom has recorded the majority of cases so far, other countries have also experienced large increases, such as Spain with 259 cases, Portugal with 191 and Germany with 150 cases.
The Venezuelan government said on Sunday that it had registered its first case of smallpox in a man who entered the country through its main airport near Caracas after arriving from Madrid.