Teenage mothers are also now at a new record low, with just 8.4 births per 1,000 people. This has been steadily declining since its peak of 50 in the early 1970s.
But the fertility rate has also fallen to an all-time low for women in their 20s, just 43.2 per 1,000 in 2021. The birth rate for people in their late 20s appears to have leveled off, at 84.6 births per 1,000 people.
Meanwhile, births to the over-30s remain high, with the early 30s now the most common age range for having a child.
In 2021, there were 16.2 births per 1,000 to over-40s, making a middle-aged mother twice as likely as a teenage mother in their respective age groups.
ONS data also released on Tuesday show that around one in four births in England and Wales were to a mother who was not born in Britain.
These second-generation immigrants represent families from all over the world, with Pakistan the most common country of origin for fathers and Romania the most common for mothers.