Multiple Sclerosis The cause of this disease is unknown, but it is considered an autoimmune disease. This dysfunction of the immune system in MS causes the fatty substance that coats and protects the nerve fibers of the brain and spinal cord (myelin) to be destroyed. The scorching heat of summer can aggravate the problem and lead to complications such as muscle stiffness, paralysis, bladder problems, sexual dysfunction, mental health problems, depression and epilepsy.
Learn all about multiple sclerosis by Dr. Pradeep Mahajan, a researcher in regenerative medicine.
Written by Tavishi Dogra | Posted: May 30, 2022 6:53 PM IST
Our nerves are lined with a protein called myelin, which serves as an insulator. Many diseases affect this coating, so they “demyelinate” the nerve. Multiple sclerosis (MS) is one of those conditions in which there is an immune-mediated attack on the myelin sheath, which causes incorrect signal transmission. As a result, the parts of the body that are controlled by parts of the nerves in the brain and spinal cord that are affected lose their function. There are different types of MS, some slowly progressive and others associated with periodic outbreaks and periods of remission. However, the different symptoms of MS are essentially the same. In most cases, the worsening of the patient’s condition over the years is due to the accumulation of deficits and the incomplete recovery of repeated episodes.
What causes multiple sclerosis?
It is not yet clear what causes MS. It can involve a combination of genetic susceptibility and non-genetic triggers, such as viruses, low vitamin D levels, or environmental factors. In many cases, the symptoms occur suddenly, usually in people between the ages of 20 and 30, and are otherwise expected. The problem is that there are no definite risk factors or even early signs to predict the onset or prevent MS. Some studies have mentioned smoking, obesity, and race as risk factors, but these cannot be considered exclusive to MS. Therefore, treatment can only be started once the disease is detected. The problem is that conventional treatment focuses primarily on symptom management.
Regenerative Medicine Approach
Dr. Pradeep Mahajan, a researcher in regenerative medicine, talks about a regenerative medicine approach to managing MS. It talks about cells, growth factors, and peptides with properties that improve nerve function and repair the environment of damaged tissues around nerves. “Add alternative therapies to magnetic field-based treatments and cell-based therapy simulations and have a holistic approach to effective and long-term management of MS,” says Dr. Mahajan.
Nuclear magnetic resonance therapy
Low frequency nuclear magnetic resonance therapy has improved motor, sensory, autonomic, and cognitive functions. In addition, long-term arrest has also been reported in the progression of the disease, which significantly improves the quality of life of patients with MS. Transcranial magnetic stimulation is also a neuromodulatory and neurostimulatory therapy that works by electromagnetic induction of an electric field in the brain. These changes help to evoke changes in the brain environment, thus improving behavioral and motor functions. The effects of these alternative therapies are cumulative and synergistic with other minimally / non-invasive modalities such as cell-based therapy.
“For conditions like MS, we think outside the box. With a holistic regenerative approach, it is possible to achieve sustained, definitive, long-term results and improve a patient’s quality of life,” concludes Dr. Mahajan.
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