Study identifies epigenetic regulator that suppresses pathogenic events in rheumatoid arthritis
Rheumatoid arthritis (RA) is characterized by chronic inflammation of the synovium, which eventually leads to the destruction of the joints. Epigenetic alteration (the mechanism of regulation of gene expression without changes in the DNA sequence), such as low levels of DNA methylation, is one of the factors that worsens the state of RA. However, the …